23 Jul BIORESPONSIVE HYDROGEL
Abstract
Disclosed herein is a cell-mediated biodegradable scaffold material for use in tissue engineering applications. Specifically disclosed is a matrix metalloproteinase-7 (MMP-7) sensitive scaffold that, in combination with relevant cell types, results in a biodegradable scaffold with degradation kinetics optimized for orthopaedic tissue engineering applications such as an implant or to replace damaged cartilage, bone, tendon/ligament, and muscle. Also disclosed are methods of synthesizing MMP-7 biodegradable hydrogels.
Year: 2010
Country: WO
Doc No: 2010123938