23 Jul Preparation method of laponite (LAP)-doped polylactic acid-glycolic acid (PLGA) nanofiber
Abstract
The invention relates to a preparation method of laponite (LAP)-doped polylactic acid-glycolic acid (PLGA) nanofiber. The method comprises the following steps of: (1) dissolving PLGA into a THF (Tetrahydrofuran)/DMF (Dimethyl Formamide) mixed solvent, and stirring for fully dissolving the PLGA to obtain a PLGA electrostatic spinning solution; (2) uniformly dispersing the LAP into the PLGA electrostatic spinning solution while stirring to obtain a PLGA/LAP electrostatic spinning solution; and (3) performing electrostatic spinning by using the PLGA/LAP electrostatic spinning solution to obtain a PLGA/LAP composite nanofiber felt and drying. The process of the method is simple, a product is easy to prepare, and the PLGA and LAP used have low costs; and the prepared LAP-doped polylactic acid-glycolic acid nanofiber has high mechanical property, high thermal stability, high blood compatibility and high biocompatibility, and has a wide application prospect in the fields of medicament carriers, tissue engineering bracket materials and the like.
Year: 2012
Country: CN
Doc No: 102505176