23 Jul Artificial bile duct bionic stent with double-layered compound structure and preparation method of artificial bile duct bionic stent
Abstract
The invention discloses an artificial bile duct bionic stent with a double-layered compound structure and a preparation method of the artificial bile duct bionic stent. The preparation method includes using biodegradable polyester as raw materials; preparing a compact membrane-shaped inner duct by a coating method; preparing a polyester outer duct with a communicated porous structure by a gelatin porogen method; and compounding the outer duct with the inner duct so as to obtain the artificial bile duct bionic stent with the double-layered compound structure. Repeatability of a preparation process is good. The inner duct of the artificial bile duct bionic stent can support bile circulation and prevent bile leakage, and the outer duct can support cell growth and regeneration to form new bile duct tissues. The artificial bile duct bionic stent is fine in biocompatibility, free of cytotoxicity and capable of realizing regeneration and repair of a bile duct, avoids secondary surgery, can be used for tissue engineering bile duct construction and bile duct coloboma repair, and has a good clinical application prospect.
Year: 2012
Country: CN
Doc No: 102641160