23 Jul Method for preparing molecular imprinting porous gel membrane for tissue engineering
Abstract
The invention provides a method for preparing a molecular imprinting porous gel membrane for tissue engineering. Bioactive molecules such as growth factor, polypeptide, protein and the like are taken as template molecules, natural polymer sodium alginate which has good biocompatibility and can be absorbed in a degradable manner is used as a basal body, water-soluble polymer or inorganic salt serves as a pore-forming agent, and a green environment-friendly aqueous-phase imprinting method is adopted to prepare the molecular imprinting porous gel membrane with the thickness controlled between 20 and 1000mu m. The method is simple to operate and does not use any toxic and harmful solvents; the adopted materials have good biocompatibility; and cell culture porous gel membrane stents with identification and slow release performances to different template molecules can be obtained according to cell culture requirements and are used for regulating cell growth, and the method has a good application prospect in the tissue engineering field.
Year: 2013
Country: CN
Doc No: 103041445