23 Jul CA-(PLA-ran-PLC-b-PEC) periodic copolymer and preparation method and application thereof
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Abstract
The invention discloses a CA-(PLA-ran-PCL)-b-PEG star amphiphilic copolymer, and a preparation method and an application thereof. The star copolymer adopts the structure as shown in the formula I, wherein R’ refers to the specification. The method comprises the following steps: 1, preparing CA-(PLA-ran-PCL); 2, carboxylation of PEG; and 3, preparing the CA-(PLA-ran-PCL)-b-PEG star copolymer. The copolymer provided by the invention has favourable biocompatibility and biological degradability, and can be applied to the field of pharmaceutical preparations and tissue engineering, particularly the field of antitumor drugs preparations or anti-cardiovascular disease drugs preparations.
Year: 2013
Country: CN
Doc No: 103073730