23 Jul Controllable hydraulic bioreactor for tissue engineering
Abstract
The utility model discloses a controllable hydraulic bioreactor for tissue engineering, comprising a tank body and a top cover. The bioreactor is characterized in that a controllable hydraulic system is arranged at the upper end of the top cover, a circulating filling system is arranged at the lower part of the tank body, a flexible diaphragm which divides a cavity formed by the tank body and the top cover into a culturing chamber and a pressurizing chamber is arranged inside the tank body, and a multi-hole shelf plate is arranged at the lower part of the culturing chamber. A hydraulic pressurizing manner and a controllable pressure relief technology are adopted by the bioreactor disclosed by the utility model so that real-time and precise regulation and control on key parameters such as pressure stimulation strength, frequency and action time can be achieved to realize the switch among a plurality of stimulation modes; and a culture fluid inlet and a culture fluid outlet are added in a culture system to realize circulating filling culture so that complexity of basic operations such as fluid changing in an engineering cartilage construction process is greatly simplified, and pollution possibility caused by repeated uncovering operations is reduced.
Year: 2013
Country: CN
Doc No: 202898395