23 Jul Method for preparing polyaspartic acid nano hydrogel felt
Abstract
The invention discloses a method for preparing a piece of polyaspartic acid nano hydrogel felt. The method comprises the following steps of: dissolving an intermediate of polyaspartic acid, namely polysuccinimide, in dimethylformamide for electrostatic spinning, so as to obtain a piece of polysuccinimide nano fiber felt; cross-linking the obtained polysuccinimide nano fiber felt by a cross-linking agent; dipping the cross-linked nano felt in a sodium hydroxide solution for hydration, washing the nano felt by using distilled water until the nano felt is neutral, deswelling the washed nano felt by using methanol, and then performing vacuum drying on the deswelled nano felt, so as to obtain the polyaspartic acid nano hydrogel felt insoluble in water. The nano hydrogel felt provided by the invention has the characteristics of nanoscale reticular structure, high water-absorbing quality, high swelling rate, excellent biocompatibility and biodegradability, and the like; and therefore, the nano hydrogel felt has a quite wide application prospect in the aspects of drug sustained release and tissue engineering as well as the aspect of water-absorbing materials.
Year: 2013
Country: CN
Doc No: 103266474