23 Jul Natural fibroin protein fiber scaffold and preparation method
Abstract
The invention relates to a natural fibroin protein fiber scaffold and a preparation method thereof. According to the invention, degumming fibroin protein fiber is dispersed into formic acid to obtain fibroin fiber dispersion liquid; sodium chloride is added in the fibroin fiber dispersion liquid to obtain a fibroin fiber-sodium chloride-formic acid mixing solution; the fibroin fiber-sodium chloride-formic acid mixing solution is volatilized to remove formic acid to obtain a fibroin fiber-sodium chloride solid; the fibroin fiber-sodium chloride-formic acid mixing solution or the fibroin fiber-sodium chloride solid are placed in a flowing water and/or organic solvent to remove sodium chloride to obtain wet fibroin fiber scaffold; and the wet fibroin scaffold is refrigerated and dried to obtain the natural fibroin protein fiber scaffold. The inner structure of the natural fibroin protein fiber scaffold takes fiber as a main part, the natural fibroin protein fiber scaffold has the advantages of high porosity amount, high penetration rate, and excellent mechanical properties, is in favor of nutrients conveying, cell migration, and tissue growth, and is the ideal tissue engineering scaffold.
Year: 2017
Country: CN
Doc No: 106581775