23 Jul Two-component polymer superfine fiber containing synthetic polypeptide and chitosan and preparation of two-component polymer superfine fiber
Abstract
The invention relates to a two-component polymer superfine fiber containing synthetic polypeptide and chitosan and preparation of the two-component polymer superfine fiber. The two-component polymer superfine fiber is prepared through the following steps: (1) preparation of spinning liquid: a mixed solvent containing volatile organic acid and volatile halogenated hydrocarbon is prepared, then hydrophobic synthetic polypeptide and chitosan are dissolved in the mixed solvent and stirred until the liquid is uniform and transparent, and the spinning liquid is obtained; (2) high-voltage electrospinning: the spinning liquid obtained in the step (1) is subjected to high-voltage electrospinning, and the two-component polymer superfine fiber containing the synthetic polypeptide and the chitosan is prepared. Compared with the prior art, the synthetic polypeptide and the chitosan both have good biocompatibility and biodegradability, so that the cost of the synthetic polypeptide fiber can be reduced after the synthetic polypeptide and the chitosan are blended, and actual application of the fiber in the fields of tissue engineering scaffolds, medical dressings, drug sustained release and the like is facilitated.
Year: 2017
Country: CN
Doc No: 106757496