High-strength chemical-physical dual-network hydrogel with self-recovery capability, and preparation method and application of hydrogel

High-strength chemical-physical dual-network hydrogel with self-recovery capability, and preparation method and application of hydrogel

Abstract

The invention discloses high-strength chemical-physical dual-network hydrogel with self-recovery capability, and a preparation method and application of the hydrogel. The high-strength chemical-physical dual-network hydrogel with the self-recovery capability is prepared from a first chemical network formed by the polymerization of hydrophilic monomers or by enabling hydrophilic macromolecules to be mixed and have a reaction, and a second physical network formed by carrying out physical crosslinking on polysaccharide and derivatives thereof, wherein the first chemical network and the second physical network are arranged in a way of being interspersed with each other. The dual-network hydrogel has high compressive strength and tensile strength, high toughness as well as good self-recovery property and fatigue resistance, and can maintain higher tensile strength and breakage elongation under the condition of having a notch. The prepared hydrogel has good mechanical property and biocompatibility, can be widely applied to the field of biological medicine, and can be used as a surface coating of a scaffold for tissue engineering, medical sponge or a medical implant.

Year:  2017

Country:  CN

Doc No:  107011609

 

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