Injectable composite gel and preparation method and application thereof

Injectable composite gel and preparation method and application thereof

Abstract

An injectable composite gel and a preparation method and an application thereof mainly relate to the field of tissue engineering. The preparation method comprises mixing a chitosan solution, a gelatinsolution and a sodium Beta-glycerophosphate solution according to the certain ratio and sequence and adding a certain amount of growth factors and seed cells to make the prepared gel have the performance of repairing multiple kinds of tissues. The injectable composite gel prepared by the method not only has a certain factor sustained release effect but also can compound various cells to provide cell support for tissue repair, thereby better adapting to the injury part, reducing inflammation, promoting migration and aggregation of the cells and differentiation of the seed cells and promoting the formation of new blood vessels and the repair of necrotic tissues. Therefore, the injectable composite gel, the preparation method and the application have broad application prospects.

Year:  2018

Country:  CN

Doc No:  108744057

 

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