23 Jul Corneal carrier material and preparation method thereof
Abstract
The invention provides a corneal carrier material and a preparation method thereof and relates to the technical field of tissue engineering. The preparation method of the corneal carrier material, provided by the invention, comprises the steps of subjecting repeated-frozen-thawed human corneal stroma homogenate to decellularizing and then carrying out treatment molding. According to the method, the process is simple and convenient, medical resources are utilized reasonably, and thus, the method is applicable to large-scale production and clinical popularization and application. According to the method, homogeneous corneal stroma homogenate is used as a raw material, and an artificial corneal carrier material is reconstructed on the basis of reserving natural extracellular matrix componentsof cornea, so that the prepared corneal support material has good optical properties, a three-dimensional structure and biocompatibility. Through removing remaining antigenic components from cornea by decellularizing, the probability of an exclusive reaction after corneal transplantation can be lowered, and the success rate of transplantation is increased.
Year: 2019
Country: CN
Doc No: 109568663