23 Jul Antibacterial hydrogel with sterilization, low bacterial adhesion and bacterial release, and preparation method and application thereof
Abstract
The invention belongs to the field of hydrogels, and particularly discloses a preparation method of an antibacterial hydrogel with sterilization, low bacterial adhesion and bacterial release, the method comprises the following steps: 1) mixing a response monomer and an epoxy monomer, and carrying out a free radical copolymerization reaction to obtain an epoxy group-containing response polymer; 2)mixing and dissolving the epoxy group-containing responsive polymer and an epoxy group-containing hydrophilic polymer in a solvent, and adding an amino group-containing bactericide to carry out epoxyring opening reaction to obtain the antibacterial hydrogel. The invention also discloses the antibacterial hydrogel with sterilization, low bacterial adhesion and bacterial release prepared by the preparation method and application thereof in wound dressing. The preparation process of the method is simple and efficient, the obtained hydrogel has comprehensive functions and good biocompatibility, has wide research prospects in the fields of biomedicine and tissue engineering, and provides a new idea for the preparation of functional materials.
Year: 2019
Country: CN
Doc No: 110330658