23 Jul Biological ink for 3D printing of artificial skin
Abstract
The invention relates to biological ink for 3D printing of artificial skin, and belongs to the technical field of tissue engineering. The biological ink comprises a component A used for constructing an epidermal layer, a component B used for constructing a corium layer and a component C used for constructing an acellular matrix scaffold, wherein the component A comprises first seed cells, first carrier hydrogel and first growth factor slow-release gel containing traditional Chinese medicine components, and the mass ratio of the first carrier hydrogel to the first growth factor slow-release gelis (60: 1)-(60: 8); and the component B comprises second seed cells, second carrier hydrogel and second growth factor slow-release gel. The traditional Chinese medicine components such as dragon’s blood and ampelopsis japonica and growth factor slow-release gel are added, and seed cells are extracted from the skin of a patient. The biological ink has good biocompatibility, can effectively promotecell proliferation and regeneration and wound healing, has good mechanical and fluidic properties, and can be used in 3D printing skin and other related fields.
Year: 2020
Country: CN
Doc No: 110772669