23 Jul TISSUE-ENGINEERING MENISCUS COMPOSITE SCAFFOLD AND PREPARATION METHOD THEREFOR
Abstract
A tissue-engineering meniscus composite scaffold (100) and a preparation method therefor. The meniscus composite scaffold (100) comprises: a scaffold (110), wherein the scaffold (110) is C-shaped and consistent with the initial shape of meniscus to be regenerated and repaired, the scaffold (110) comprises a plurality of first degradable polymer fibers (111) extending in the circumferential direction of the scaffold (110) and a plurality of second degradable polymer fibers (112) extending in the radial direction of the scaffold (110), and the first degradable polymer fibers (111) and the second degradable polymer fibers (112) arranged crosswise in multiple layers to form a frame structure body having a plurality of first pores; and a matrix material (120) compounded inside the plurality of first pores of the scaffold (110) to form meniscus composite scaffold (100) having a plurality of second pores. The meniscus composite scaffold (100) has excellent mechanical properties and biocompatibility, and can provide an excellent microenvironment required for cell growth, thereby enabling newborn meniscus to have excellent shape, structure, mechanical properties, and physiological functions.
Year: 2020
Country: WO
Doc No: 2020042674