23 Jul
Abstract
PURPOSE:To produce a large amount of a new nonselective type endothelin receptor from an animal except rat. CONSTITUTION:A nonselective type endothelin receptor (bovine ETB endothelin receptor) is isolated from a bovine lung and purified to elucidate its base sequence and amino acid sequence and to produce bovine ETB endothelin receptor by genetic engineering. Spread from elucidation of mechanism of ischemic tissue disorder to therapeutic agent, diagnosticum and preventive can be expected from analysis of endothelin receptor having plural subtypes.
Year: 1993
Country: JP
Doc No: H05310793