23 Jul 3D printing based degradation-controllable bone tissue engineering scaffold and preparation method
Abstract
The invention discloses a 3D printing based degradation-controllable bone tissue engineering scaffold and a preparation method thereof and solves the problems that precise design and manufacture of amicroporous structure cannot be guaranteed by a bone defect repairing material and the material degradation speed cannot be regulated effectively in the prior art. The scaffold is of a porous structure, porosity is 60%-95%, wire diameter of a pore wall support material is 100-800 mu m, and the scaffold is prepared from an ink raw material layer by layer by printing or prepared from at least two different ink raw materials in a layered manner by printing. The method comprises the following steps: preparing the ink raw material for 3D printing; establishing a model, performing hierarchical slicing on the established model, inputting the designed 3D model into a 3D jet printer, performing layer-by-layer printing to precisely form a target green body, and calcining the green body to obtain degradation-controllable bioceramic. By means of the degradation-controllable bone tissue engineering scaffold, combination and assembly of materials with different degradation speeds in 3D space can berealized, precise design forming of the microporous structure can be guaranteed, and the material degradation speed is regulated effectively.
Year: 2018
Country: CN
Doc No: 108187149