23 Jul 3D printed PCL-PDA-BMP2 bone tissue engineering scaffold and preparation method thereof
Abstract
The invention discloses a 3D printed PCL-PDA-BMP2 bone tissue engineering scaffold and a preparation method thereof. The 3D printed PCL-PDA-BMP2 bone tissue engineering scaffold is prepared accordingto the following steps: adopting a fusion extruding forming type 3D printing technology for extruding PCL and forming fiber bundles and preparing a 3D printed PCL scaffold through a splicing frameworkof the fiber bundles; forming a PDA coating by automatically polymerizing dopamine on the fiber surface of the 3D printed PCL scaffold, thereby preparing a 3D printed PCL-PDA scaffold; lastly, soaking the acquired 3D printed PCL-PDA scaffold in a BMP2 solution, thereby acquiring the 3D printed PCL-PDA-BMP2 bone tissue engineering scaffold. The scaffold prepared according to the invention has theadvantages of simple and reliable structure, controllable appearance and microstructure, reliable mechanical properties and controllable ion release property, and can be used for restorative treatmentof bone trauma, bone tumors and bone defect after bone infection.
Year: 2018
Country: CN
Doc No: 108904880