23 Jul 3D printed all-through tubular hydrogel support and preparation method thereof
Abstract
The invention discloses a 3D printed all-through tubular hydrogel support and a preparation method thereof. The method comprises the following steps that a, a polyion type/thermo-sensitive type complex solution is prepared and poured into a 3D printing material cylinder; b, printing parameters are set, and printing is conducted on a low-temperature platform to obtain a heat-reversible composite hydrogel support; c, the support is soaked in an ionic cross-linking agent aqueous solution for a period of time and then taken out; and d, after the edge tail end of the support is removed and then thesupport is soaked in deionized water for thermal washing treatment to obtain the hydrogel support with an all-through tubular structure. According to the support and the method, based on the difference of the thermal stability of the composite hydrogel before and after ion crosslinking, the spatial effect of 3D printing and the time effect of ion diffusion are combined, the process is simple, theprepared tubular hydrogel support has good structural connectivity and size regulation and control, and has a potential application prospect in the field of vascular tissue engineering.
Year: 2019
Country: CN
Doc No: 110421835