23 Jul 3D bioprinting silk fibroin based tissue engineering scaffold and preparation method and application thereof
Abstract
The invention discloses a 3D bioprinting silk fibroin based tissue engineering scaffold and a preparation method and application thereof, and belongs to the technical field of biomedical materials. Used silk fibroin, gelatin, hydroxyapatite and hyaluronic acid all have excellent biocompatibility, biodegradability and biological activity, wherein the hydroxyapatite is a main inorganic constituent of a human body and animal bones, certain solubility is achieved in vivo to participate in human metabolism, stimulating and inducing effects are achieved on osteoblasts, and the repair of defected bone tissue is accelerated. Silkworm cocoon is used as a raw material, the price is low, source is wide, the silkworm cocoon is non-toxic and harmless to the human body, the silk fibroin based tissue engineering scaffold has a short material preparation process, convenient processing and good formability, and thus the silk fibroin based tissue engineering scaffold has a very broad application prospect in the field of biomedical bone tissue regeneration and repair.
Year: 2020
Country: CN
Doc No: 110639060